BIRC5, baculoviral IAP repeat containing 5, 332

N. diseases: 199; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 Biomarker group LHGDN [Clinical significance of the relationship between expression of survivin and effects of neoadjuvant chemotherapy in locally advanced breast cancer]. 18701842 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 AlteredExpression group LHGDN Growth factor-dependent regulation of survivin by c-myc in human breast cancer. 17170079 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 Biomarker group LHGDN Altered cytoplasmic-to-nuclear ratio of survivin is a prognostic indicator in breast cancer. 18451232 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 AlteredExpression group LHGDN Upregulation of survivin by leptin/STAT3 signaling in MCF-7 cells. 18242580 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 AlteredExpression group LHGDN Peroxisome proliferator-activated receptor gamma agonists promote TRAIL-induced apoptosis by reducing survivin levels via cyclin D3 repression and cell cycle arrest. 15569667 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 AlteredExpression group BEFREE In addition, BIRC5 expression may induce breast tumor proliferation by promoting genetic instability. 18181175 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 AlteredExpression group LHGDN Changes of survivin mRNA and protein expression during paclitaxel treatment in breast cancer cells. 17393113 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 Biomarker group LHGDN Expression of survivin and its splice variants survivin-2B and survivin-DeltaEx3 in breast cancer. 15611790 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 Biomarker group LHGDN Molecular dependence of estrogen receptor-negative breast cancer on a notch-survivin signaling axis. 18593928 2008
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 Biomarker group LHGDN Detection of autoantibodies to survivin and livin in sera from patients with breast cancer. 16026775 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 Biomarker group CTD_human Delta9-tetrahydrocannabinol inhibits cell cycle progression in human breast cancer cells through Cdc2 regulation. 16818634 2006
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 GeneticVariation group LHGDN Distinct expression of Survivin splice variants in breast carcinomas. 16142334 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 Biomarker group CTD_human Survivin expression is regulated by coexpression of human epidermal growth factor receptor 2 and epidermal growth factor receptor via phosphatidylinositol 3-kinase/AKT signaling pathway in breast cancer cells. 16322251 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.400 GeneticVariation group LHGDN Do the survivin (BIRC5) splice variants modulate or add to the prognostic value of total survivin in breast cancer? 16873289 2006
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.390 AlteredExpression group LHGDN Aurora A, Aurora B and survivin are novel targets of transcriptional regulation by histone deacetylase inhibitors in non-small cell lung cancer. 18708766 2008
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.390 AlteredExpression group LHGDN The role of survivin on overall survival of non-small cell lung cancer, a meta-analysis of published literatures. 18192073 2008
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.390 Biomarker group LHGDN Influence of SiRNA targeting survivin on chemosensitivity of H460/cDDP lung cancer cells. 18652770 2008
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.390 Biomarker group CTD_human Cisplatin activates Akt in small cell lung cancer cells and attenuates apoptosis by survivin upregulation. 15981204 2005
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.390 AlteredExpression group LHGDN Up-regulation of survivin mRNA might be a marker for non-invasive detection of non-small cell lung cancer rather than for prognosis. 18630507 2008
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.390 Biomarker group LHGDN Quantitative detection of survivin in malignant pleural effusion for the diagnosis and prognosis of lung cancer. 18824294 2009
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.390 AlteredExpression group LHGDN Induction of death receptor 5 and suppression of survivin contribute to sensitization of TRAIL-induced cytotoxicity by quercetin in non-small cell lung cancer cells. 17548900 2007
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.390 Biomarker group CTD_human Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin. 16108013 2006
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.390 AlteredExpression group LHGDN Tumor specific expression of survivin-2B in lung cancer as a novel target of immunotherapy. 15829330 2005
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.390 Biomarker group LHGDN COX-2-dependent stabilization of survivin in non-small cell lung cancer. 14597555 2004
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.390 Therapeutic group CTD_human Small interfering RNA targeting survivin sensitizes lung cancer cell with mutant p53 to adriamycin. 16108013 2006